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Senior Scientist In Vivo Pharmacology

Reference Number: 2768
Location: MA

Our client is a rapidly growing, specialty biopharmaceutical company.  They have retained us to assist them in their search for a Senior Scientist In Vivo Pharmacology.

The Senior Scientist In Vivo Pharmacology will be responsible for designing, implementing and performing in vivo pharmacology studies in rodent models of disease. The individual will also be expected to make significant scientific contributions to the Pharmacology group and project teams.

Major tasks and responsibilities will include:

  • Conducts preclinical in vivo pharmacology studies to evaluate novel oligonucleotide therapeutics from design, study initiation and completion through to data analysis, interpretation and communication of results to project teams and relevant groups.
  • Assess disease relevant phenotypic and functional effects.  Performs analysis for RNA and protein end-points such as qualitative PCR, Westerns and ELISA’s.
  • Provides operational support for preclinical in vivo studies conducted with external contractors and academic collaborators.
  • Contributes both technical and scientific knowledge to drive innovation and advance projects forward.
  • Works both independently and collaboratively in small cross-functional teams.
  • Reports to the Head of In Vivo Pharmacology.

We seek candidates with the following qualifications:

  • PhD in a relevant life sciences discipline is required with a minimum of 2 years of relevant experience in the pharmaceutical industry.
  • At least 5 years of experience handling and working with rodents, specifically mice.
  • Highly proficient with multiple routes of administration (s.c., i.m., and i.t. preferred), blood sampling techniques, necropsies and tissue collections.
  • Experience analyzing RNA and protein samples prepared from tissues using qRT-PCR, Westerns and/or ELISA techniques.
  • Experience managing or providing operational support for in vivo studies conducted with contract research organizations or academic collaborators is highly desired.
  • Experience writing protocols and interfacing with IACUC is highly desired.
  • Experience with oligonucleotide therapeutics is an advantage.
  • Proven abilities to multi-task, work independently and productively with limited supervision and also collaboratively as part of an interdisciplinary team.
  • Excellent interpersonal and oral/written communication skills.


Do you have the skills and experience we seek and want to advance your career with one of the world’s leading companies? If so, please email your resume as a Word attachment to us, reference 2768. No calls or faxes, please. Include your daytime phone number and we will contact you confidentially or reply to your email.